Scientists rethink Alzheimer's, diversifying the drug search

Scientists are rethinking Alzheimer’s disease in the wake of a string of disappointing drug failures.

For years, the goal was to stop buildup of sticky plaques that are a hallmark of the mind-robbing disease. The drug flops made clear other things are playing a role, too.

Now there’s a new focus — diversity — as researchers explore multiple novel ways of attacking a disease too complex for a one-size-fits-all solution.

It’s not clear if these fresh starts will pan out. But high on the list are ways of targeting immune cells in the brain, fighting inflammation, even asking if simmering infections play a role.